Pharmaceutical Organic Chemistry 4th Semester Imp Questions With Answer || All Unit Notes || 40 Plus MCQ Questions

 Pharmaceutical organic chemistry 4th semester imp questions  with answer || all unit notes || 40 plus MCQ questions.

                             Mr. Rahul Nagesh 

B. Pharma 4th Sem pharmaceutical organic chemistry Imp Questions (CSVTU)

Previous year question paper 2022-23
                                   
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                             All Unit Notes
                                         

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Stereo isomerism
Optical isomerism -

Optical activity, enantiomerism, diastereoisomerism, meso compounds

Elements of symmetry, chiral and achiral molecules

DL system of nomenclature of optical isomers, sequence rules, RS system of nomenclature of optical isomers

Reactions of chiral molecules

Racemic modification and resolution of racemic mixture. Asymmetric synthesis: partial and absolute


Geometrical isomerism
Nomenclature of geometrical isomers (Cis Trans, EZ, Syn Anti systems)

Methods of determination of configuration of geometrical isomers.

Conformational isomerism in Ethane, n-Butane and Cyclohexane. Stereo isomerism in biphenyl compounds (Atropisomerism) and conditions for optical activity.

Stereospecific and stereoselective reactions


Heterocyclic compounds:
Nomenclature and classification

Synthesis, reactions and medicinal uses of following compounds/derivatives

Pyrrole, Furan, and Thiophene

Relative aromaticity and reactivity of Pyrrole, Furan and Thiophene



Synthesis, reactions and medicinal uses of following compounds/derivatives

Pyrazole, Imidazole, Oxazole and Thiazole.

Pyridine, Quinoline, Isoquinoline, Acridine and Indole. Basicity of pyridine

Synthesis and medicinal uses of Pyrimidine, Purine, azepines and their derivatives



Reactions of synthetic importance
Metal hydride reduction (NaBH4 and LiAlH4), Clemmensen reduction, Birch reduction, Wolff Kishner reduction.

Oppenauer-oxidation and Dakin reaction.

Beckman rearrangement and Schmidt rearrangement.

Claisen-Schmidt condensation


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